Back to Search
Start Over
Abstracts of the First Meeting of the Society for Intestinal Microbial Ecology and Disease, Boston, Massachusetts, 1983
- Source :
- Models of Anaerobic Infection ISBN: 9789400960565
- Publication Year :
- 1984
- Publisher :
- Springer Netherlands, 1984.
-
Abstract
- During enterohepatic circulation conjugated steroids are hydrolyzed by intestinal bacteria, further metabolized mainly by anaerobic bacteria, reabsorbed, reconjugated and delivered to the blood for renal excretion. 21-Dehydroxlylation of tetrahydrodeoxycorticosterone (THCOD) to pregnanolone is performed exclusively by Eubacterium lentum, a normal inhabitant of the intestinal flora. The concentration of E. lentum in feces can be determined from the highest dilution of fresh voided stool capable of 21-dehydroxylating THDOC. Such studies revealed that the concentration increases from 106/g wet feces during the first year of life to 108/g feces in the 7th and 8th decade. Colonization appears to be independent of diet since the organisms are present in babies whether breast-fed or on formula, in subjects on a “Western diet” and in Africans consuming a diet low in meat and fat.
Details
- ISBN :
- 978-94-009-6056-5
- ISBNs :
- 9789400960565
- Database :
- OpenAIRE
- Journal :
- Models of Anaerobic Infection ISBN: 9789400960565
- Accession number :
- edsair.doi...........cb3debdea506ce267776a72288aa0c54