694Metabolic conditions have high prevalence in CHamoru men in a hyperuricemia feasibility study in Guam

Background One-third of adults in the U.S. have metabolic syndrome, a combination of risk factors of chronic diseases such as heart disease, kidney disease, diabetes, and gout. These diseases are a burden for ethnic minorities, including Pacific Island peoples. Here, the metabolic conditions were described for a group of Pacific Island people, the CHamorus or natives of Guam, a U.S. Territory in the Mariana Islands in the Western Pacific. Methods A cross-sectional survey was conducted in Guam from August 2019 to January 2020. A non-random sample of 152 adults, ≥18 years old, with CHamoru ancestry were recruited and consented. Information collected included socio-demographics, metabolic history, lifestyle behaviors, height and weight, blood pressure, and non-fasting blood and urine. Statistical analyses included frequencies of metabolic conditions and Pearson’s Chi-square test for gender differences, alpha=0.05. Results Of the 152 CHamorus, 49.3% were male, 50% were female, and 0.7% was transgender. The mean age was 43±15.1 years. Mean education was 14.4±3.6 years and hyperuricemia he majority (69.7%) pursued postsecondary studies. Self-reported metabolic conditions included: diabetes (19.7%), gout (28.9%), hypertension (34.9%), dyslipidemia (17.8%), and heart conditions (9.9%). Compared to females, more males reported gout (40.5% versus 18.7%; P=.003) and measured to be hypertensive (48% versus 21.1%; P Conclusion Metabolic conditions were common among CHamorus, though gout, hypertension, hyperuricemia, and obesity were predominant in the men. Key messages Strategies to reduce the burden of metabolic conditions may be targeted to CHamoru men in this community.