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Biogenic Silver Nanoparticles Embedded Polyvinyl Alcohol Nanofibrous Scaffolds Avert Tumour and Bacterial Growth

Authors :
B. S. Unnikrishnan
T. T. Sreelekha
G.U. Preethi
Manu M. Joseph
R. Shiji
Source :
Current Science. 116:1735
Publication Year :
2019
Publisher :
Current Science Association, 2019.

Abstract

This communication describes a carefully designed strategy which blends biogenic silver nanoparticles with PVA scaffolds to fabricate SNP@PVA electrospun scaffolds with admirable physico-chemical properties. The hybrid scaffold demonstrated cyto-compatibility and hemo-compatibility with no adverse effects on the surrounding cells, as demonstrated by multiple assays. The growth of cancer cells was greatly prevented by SNP@PVA scaffolds, while allowing growth of normal cells. The outstanding antimicrobial features of the scaffold can be attributed to the presence of silver na-noparticles and proves the use of SNP@PVA for bio-medical applications.

Details

ISSN :
00113891
Volume :
116
Database :
OpenAIRE
Journal :
Current Science
Accession number :
edsair.doi...........c99ebb81fdc1b884fc889ac4f5957d04
Full Text :
https://doi.org/10.18520/cs/v116/i10/1735-1741