Absence of elevated serum tryptase in rocuronium-induced anaphylaxis during discectomy under general anesthesia: A case report

A 43-year-old female patient, who had previously undergone surgery under general anesthesia without any problems, was scheduled for discectomy. Propofol and rocuronium were injected sequentially to induce general anesthesia. Twenty minutes after the rocuronium injection, severe hypotension, tachycardia and bronchospasm developed, and delayed skin rashes appeared. The operation was cancelled. No postoperative complications were evident, and the patient was discharged from the hospital. Serum tryptase value at the time of anaphylaxis was within normal ranges. But skin prick test and intradermal test was found to anaphylaxis caused by rocuronium after six weeks.