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Effects Metilprednizalonium, Motor of Training and a Combination in Change Parameters of M-Response in the Gastrocnemius Muscle of Rats During Acute and Chronic Period After Experimental Spinal Cord Injury
- Source :
- BioNanoScience. 7:64-66
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- An increasing number of treatments for spinal cord injury (SCI) out of the laboratories and in clinical trials pass. Many of them are used as soon as possible after the injury with the hope of weakening the secondary damage and maximize the preservation of nerve tissue. The aim of the study was to evaluate the effects metilprednizalonium and motor training at an experimental spinal cord injury in rats. To investigate the status of the peripheral neuromuscular system registered motor response (M-response) muscles. In the early period after spinal cord injury was observed, a decrease of the maximum amplitude of M-response. With that, in the group of animals with the introduction of metilprednizalonium, amplitude of M-response was higher than that without drug therapy. Combined therapy metilprednizalonium and motor training has a positive effect on the recovery of motor function in chronic period after contusion spinal cord injury in rats.
- Subjects :
- 0301 basic medicine
030103 biophysics
medicine.medical_specialty
Motor training
business.industry
Period (gene)
Biomedical Engineering
Bioengineering
M response
medicine.disease
Peripheral
03 medical and health sciences
Gastrocnemius muscle
0302 clinical medicine
Physical medicine and rehabilitation
Anesthesia
medicine
Combined therapy
business
Spinal cord injury
030217 neurology & neurosurgery
Maximum amplitude
Subjects
Details
- ISSN :
- 21911649 and 21911630
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- BioNanoScience
- Accession number :
- edsair.doi...........c89596208d80b04c184a841ff58aeef1