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The Relationship of adiponectin level andADIPOQgene variants with BMI among young adult women
- Source :
- Dermato-Endocrinology. 10:e1477902
- Publication Year :
- 2018
- Publisher :
- Informa UK Limited, 2018.
-
Abstract
- The current study examined the effect of single nucleotide (SNPs) polymorphisms in the ADIPOQ gene (I146T and G276T) on body mass index (BMI) of young adult women. The women were divided into underweight, normal, overweight and obese according to BMI. The circulating levels of adiponectin were measured using commercially available ELISA kits. Genetic polymorphisms were genotyped using the PCR-RFLP method. G276T and I164T SNPs are common in the examined population as the frequency of G allele of 276 SNP was 54.8% and for the T allele of 164 SNP it was 41.7%. Circulating adiponectin levels were related to BMI and were lowest in the obese versus overweight, normal weight and underweight groups (p
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
Population
030209 endocrinology & metabolism
Single-nucleotide polymorphism
Dermatology
ADIPOQ Gene
Overweight
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
education
education.field_of_study
Adiponectin
business.industry
nutritional and metabolic diseases
medicine.disease
Obesity
030104 developmental biology
Endocrinology
medicine.symptom
Underweight
business
Body mass index
Subjects
Details
- ISSN :
- 19381980
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Dermato-Endocrinology
- Accession number :
- edsair.doi...........c804a0d221ccea83c08d313e83c8e912