Antimicrobial Activity and Chemical Constituents of the Essential Oils from Root, Leaf and Aerial Part ofNepeta asterotrichafrom Iran

The chemical constituents from the root, leaf and aerial part of Nepeta asterotricha Rech.f., growing in Iran, were obtained by hydrodistillation and analyzed by GC and GC-MS. The root oil was characterized by higher amount of 4aα, 7β, 7aα- nepetalactone ( 26.25 %), linalool ( 10.20 %), 1,8-cineole (10.18 %) and terpinen-4-ol (9.18 %). Thirty-two constituents representing 97.58 % of the chromatographical leaf oil were identified of which 1,8-cineole (21.01 %), 4aα, 7β, 7aα- nepetalactone (15.05 %), terpinen-4-ol (14.33 %) and linalool (7.69 %) were the major components. The main components of the aerial part oil were 1,8-cineole (26.12 %), terpinen-4-ol (14.83 %), 4aα, 7α, 7β- nepetalactone (8.65 %) and cis-sabinene hydrate (8.58 %). The antimicrobial effects of root, leaf and aerial part essential oils from N. asterotricha were studied against seven Gram-positive and Gram-negative bacteria and three fungi by disc diffusion method. The results of the bioassays showed the interesting antimicrobia...