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Podosomes are disrupted in PAPA syndrome
- Source :
- Blood. 123:2597-2599
- Publication Year :
- 2014
- Publisher :
- American Society of Hematology, 2014.
-
Abstract
- In this issue of Blood , Starnes et al describe a novel proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1) mutation that is responsible for pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome. This helps us understand how PSTPIP1 regulates podosome and filopodia formation and migration of macrophages. 1
Details
- ISSN :
- 15280020 and 00064971
- Volume :
- 123
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi...........c7d817f6020bde69462739530f4b518b