A new near-infrared ratiometric fluorescent probe for hydrazine

It is important to develop fluorescent probes for rapid, selective, and sensitive detection of highly toxic hydrazine in both environmental and biological science. In this text, under mild conditions, a novel near-infrared (NIR) ratiometric and on–off fluorescent probe 1 was synthesized based on hemicyanine and coumarin derivatives, which can detect hydrazine with high selectivity and anti-interference over other amines, biological species, anions and metal ions. The limit of quantification (LOQ) value was 0–400 μM and the detection limit could be as low as 560 nM.