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HIF-1α and VEGF Expression in Fracture Healing

Authors :
Hyun-Chul Shon
Kang-Sik Lee
Jae-Suk Chang
Jung Jae Kim
Seok-Won Kim
Jung-Hwa Kim
Source :
The Journal of the Korean Orthopaedic Association. 43:479
Publication Year :
2008
Publisher :
The Korean Orthopaedic Association, 2008.

Abstract

Purpose: To elucidate the relation between fracture healing and angiogenesis, we checked expression of Hypoxia-inducible factor (HIF) and Vascular endothelial growth factor (VEGF) in hypoxic cell cultures and the callus from a rat femur fracture model. Materials and Methods: Human osteoblasts, chondrocytes, and rat ST2 cells were cultured in DME/F12 media with 10% FBS. Hypoxic DME/F12 media (PO2

Subjects

Subjects :
Femur fracture
medicine.diagnostic_test
Angiogenesis
business.industry
Immunocytochemistry
Bone healing
Anatomy
Vascular endothelial growth factor
Andrology
chemistry.chemical_compound
chemistry
Western blot
Cell culture
Callus
medicine
business

Details

ISSN :
12262102
Volume :
43
Database :
OpenAIRE
Journal :
The Journal of the Korean Orthopaedic Association
Accession number :
edsair.doi...........c770b0571c723528676562e2197c07c8
Full Text :
https://doi.org/10.4055/jkoa.2008.43.4.479
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