INO-1001, a novel poly(ADP-ribose) polymerase inhibitor reduces myocardial and endothelial reperfusion injury after orthotopic heart transplantation

INO-1001, A NOVEL POLY(ADP-RIBOSE) POLYMERASE INHIBITOR REDUCES MYOCARDIAL AND ENDOTHELIAL REPERFUSION INJURY AFTER ORTHOTOPIC HEART TRANSPLANTATION G. Szabo, N. Stumpf, C. Flechtenmacher, Z. Zsengeller, S. Mandera, U. Heger, C.F. Vahl, C. Szabo, S. Hagl, Department of Cardiac Surgery, University of Heidelberg, Heidelberg, BW, Germany; Institue of Pathology, University of Heidelberg, Heidelberg, BW, Germany; Inotek Pharmaceuticals, Beverly, MA, Germany