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Development of Poly(Vinyl Alcohol)-Collagen-Hydroxyapatite Nanohybrids for Tissue Grafting
- Source :
- Key Engineering Materials. :329-332
- Publication Year :
- 2007
- Publisher :
- Trans Tech Publications, Ltd., 2007.
-
Abstract
- Poly(vinyl alcohol) (PVA) was introduced during in situ synthesis of hydroxyapatite (HA) in neutral collagen (COL) solution and final PVA-COL-HA nanohybrids were achieved via sequential steps including gelation by fibrillogenesis, freezing-thawing physical crosslinking, removal of unreacted residues and dehydration. This method is expected to endow the pure PVA with good bioactivity and meanwhile the presence of elastic PVA would improve the properties of COL-HA composites. The phase, microstructure and possible molecular interactions of the achieved PVA-COL-HA nanohybrids were analyzed by using X-ray diffraction, Fourier transform infra-red spectroscopy and scanning electron microscopy. The results indicate that the inorganic phase is poorly crystallized apatite with a nanometer size due to the confinement of organic macromolecules which forms a network structure.
- Subjects :
- In situ
Vinyl alcohol
Materials science
integumentary system
Scanning electron microscope
Mechanical Engineering
Fibrillogenesis
macromolecular substances
Microstructure
Apatite
chemistry.chemical_compound
Chemical engineering
chemistry
Mechanics of Materials
visual_art
Phase (matter)
Polymer chemistry
visual_art.visual_art_medium
General Materials Science
Macromolecule
Subjects
Details
- ISSN :
- 16629795
- Database :
- OpenAIRE
- Journal :
- Key Engineering Materials
- Accession number :
- edsair.doi...........c63127ca4dc2f52aca3bafe3264166f4
- Full Text :
- https://doi.org/10.4028/www.scientific.net/kem.330-332.329