Clinical Application of ICP Monitoring Based on FVEP in Treatment of Patients with Hypertensive Intracerebral Hemorrhage

ObjectiveTo investigate the application value of flash visual evoked potential (FVEP) in the monitoring of the noninvasive intracranial pressure (nICP) in patients with hypertensive intracerebral hemorrhage (HICH).MethodsOne hundred and two patients with HICH were randomly divided into FVEP nICP monitoring group (experimental group) and the non-monitoring group (control group). The experimental group were examined lumbar puncture immediately after intracranial pressure was monitored by FVEP. Mannitol was used to dehydration treatment of intracranial hypertension patients. The serum concentrations of creatinine and urea nitrogen were recorded to assess the renal function. Using the mannitol usage to evaluate the value of FVEP nICP monitoring techniques in guiding the adjustment of dehydrating agent. The Glasgow prognosis scores (GOS) were evaluated for patients' prognosis between two groups. ResultsThere was no statistical significance between FVEP nICP measurement and lumbar puncture intracranial pressure measurement (195.76 ±13.24 mmH2O vs 197.04 ±11.98 mmH2O, P>0.05). The use of mannitol in the experimental group was significantly lower than that in the control group (P< 0.05), and the serum creatinine and urea nitrogen concentrations in the two groups were not statistically significant (P> 0.05). The cure rate of the experimental group was higher than that of the control group (χ2=3.889, P=0.048). ConclusionFVEP nICP monitoring technology could replace invasive intracranial pressure monitoring technology in monitoring intracranial pressure for HICH patients. The application of FVEP nICP technique can reduce the dosage of dehydrating mannitol and improve the prognosis of patients with HICH.