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Photochemical addition of cyclic ethers/acetals to olefins using BuOO Bu: Synthesis of masked ketones/aldehydes and diols
- Source :
- Tetrahedron. 76:131557
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- A fast photochemical C–C bond formation between cyclic ethers/acetals and olefins using di-tert-butyl peroxide (DTBP) was developed. This method provides easy access to 2-substituted cyclic ethers, and 2- or 4-substituted cyclic acetals. Acyl/formyl groups or diols can be obtained by the hydrolysis of the 2- or 4-substituted cyclic acetals, respectively. The reactions proceeded at room temperature and gave the expected products in good to excellent yields; efficient reactions were completed within 0.5 h at room temperature in >95% yield.
Details
- ISSN :
- 00404020
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- Tetrahedron
- Accession number :
- edsair.doi...........c531070272cbe1ffe4e22a6791687b50