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ChemInform Abstract: Synthesis of Sterically Congested 1,3,4-Oxadiazole Derivatives from Aromatic Carboxylic Acids, N,N-Dicyclohexylcarbodiimide and (N-Isocyanimino)triphenylphosphorane
- Source :
- ChemInform. 42
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- Reactions of (N-isocyanimino)triphenylphosphorane with N,N-dicyclohexylcarbodiimide in the presence of aromatic (or heteroaromatic) carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions, and no side reactions were observed.
Details
- ISSN :
- 09317597
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........c4ac466041bfaa7d1bbcca3c3b641dab