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Reactivation of Tuberculosis during Dual Therapy with Pegylated Interferon and Ribavirin for Chronic Hepatitis C about a Case

Authors :
A. W. Ndjitoyap
M.J. Lohoues Kouacou
Siaka Koné
Dramane Soro
Constant Assi
Amadou Ouattara
Anassi Jean-Baptiste Okon
D. Diallo
K. E. Allah
Benoît-Mathieu Camara
Source :
Open Journal of Gastroenterology. :83-87
Publication Year :
2015
Publisher :
Scientific Research Publishing, Inc., 2015.

Abstract

The infection by the virus of the hepatitis C can be associated with other infectious diseases, including the viral and bacterial infections of which the tuberculosis. The infection to Mycobacterium tuberculosis can remain latent during several years and show itself during a state of immunesuppression. The role of the antiviral treatment in the reactivation of the tuberculosis is debated. We bring back an observation of tubercular reactivation during dual therapy with pegylated interferon and ribavirin for a viral chronic hepatitis C. A virologique answer slow was obtained in the 40th week, as well as the reactivation of the tuberculosis. The tuberculosis was of ganglionic localization at our patient. The antituberculous treatment was established while maintaining the treatment. The evolution of the tuberculosis under treatment was favorable but for the VHC, we noted a virologique answer with premature relapse.

Details

ISSN :
21639469 and 21639450
Database :
OpenAIRE
Journal :
Open Journal of Gastroenterology
Accession number :
edsair.doi...........c46a2abdb170b3828200d9ad320127a9
Full Text :
https://doi.org/10.4236/ojgas.2015.57014