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Natural history and progression of atherosclerotic renal vascular stenosis
- Source :
- Nephrology. 15:S204-S209
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- SUMMARY OF THE EVIDENCE Atherosclerotic renal vascular disease is a progressivedisease, with high grade stenosis (>60%), systolic hyperten-sion (>160 mmHg) and diabetes associated with fasterprogression. Abnormal baseline creatinine and bilateralstenosis are associated with greater likelihood of deteriora-tion of renal function. Patients with ARVD have increasedmortality and morbidity, particularly from cardiovasculardisease. WHAT DO THE OTHER GUIDELINES SAY?Kidney Disease Outcomes Quality Initiative: No recom-mendation. UK Renal Association: No recommendation. Canadian Society of Nephrology: No recommendation. European Best Practice Guidelines: No recommendation. International Guidelines: No recommendation. SUGGESTIONS FOR FUTURE RESEARCH 1. Perform a large prospective study with ultrasound sur-veillance to look at risk factors for progression.2. Investigate the variability in progression rate when dif-ferent imaging modalities are used for follow up.3. Investigate the influence of lifestyle changes, statins,renin-angiotensin system blockade alone or in combinationon stenosis progression.
Details
- ISSN :
- 14401797 and 13205358
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Nephrology
- Accession number :
- edsair.doi...........c40df57d3f12e2fcd386ca48286d05ba