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Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation

Authors :
Jun Wang
Jürgen Harder
Meino Rohlfs
Neil Warner
Shauni Doms
Daniela Aust
Gustavo B. Baretton
Julia Mayerle
Judith R. Kelsen
Thomas Kurth
Anne Strigli
Shreya Gopalakrishnan
Jochen Hampe
Jelka Hartwig
Christoph Klein
Fabian Rost
Andreas Linkermann
Michael Forster
Kenneth Peuker
Marijana Basic
Philipp Arnold
Pia Hönscheid
Britt-Sabina Petersen
Michael H. Muders
Helga-Paula Török
André Bleich
Tobias Schwerd
Ryusuke Nambu
Aleixo M. Muise
John F. Baines
Sebastian Zeissig
Yvonne Zeissig
Andre Franke
Source :
Science Immunology. 6
Publication Year :
2021
Publisher :
American Association for the Advancement of Science (AAAS), 2021.

Abstract

Inflammatory bowel disease (IBD) is characterized by inappropriate immune responses to the microbiota in genetically susceptible hosts, but little is known about the pathways that link individual g...

Details

ISSN :
24709468
Volume :
6
Database :
OpenAIRE
Journal :
Science Immunology
Accession number :
edsair.doi...........c38c385e5064dbfd6c7c9663ee44593a
Full Text :
https://doi.org/10.1126/sciimmunol.abf7473