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ChemInform Abstract: Synthesis, Antibacterial and Antifungal Activities of Some Carbazole Derivatives

Authors :
Cheng-He Zhou
Lin-Ling Gan
Fei-Fei Zhang
Source :
ChemInform. 41
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.

Details

ISSN :
15222667 and 09317597
Volume :
41
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........c2bcb5733046214d1a5cbf0b91972ef2