Association of dietary Eicosapentaenoic acid (EPA) & Docosahexaenoic acid (DHA) and marker of oxidative stress, superoxide dismutase (SOD) in obese women athletes: A cross-sectional study

Background: omega 3 fatty acid metabolites (Eicosapentaenoic acid and Docosahexaenoic acid) are essential fatty acids which showed significant roles for making balance on inflammatory and oxidative stress markers. The aim of present study is to investigate the correlation of dietary EPA/DHA with some of the biochemical markers of oxidative stress such as SOD, hs-CRP, and BMI. Method: this study used to on women people with mean ages 37.81± 7.65. The women are overweight and obese with mean of BMI with mean ± SD 29 ± 3.8. Demographic data of people by filling a form. Weight was assessed by Seca scale and CRP, SOD and Adiponectin of people were measured by obtaining blood from people. Results. There is observed significant association between EPA and SOD in crude model, although this correlation no observed after adjusting potential cofounder including fat, energy intake, BMI, Caffeine Consumption and education with β ± SE (1.29, p-value Consumption and education with β ± SE (3.38, p-valueConclusionOur study showed significant association between EPA and DHA and SOD before adjusting potential cofounder, nevertheless did not show a significant association between DHA and EPA and CRP, Adiponectin and SOD plasma concentration.