Role of pancreatic duct fusion anomalies as risk factor for post-ERCP pancreatitis

s / Pancreatology 15 (2015) S1eS141 S60 Patients&methods:We evaluated 234 patients with first onset of SAP appears in last twenty fourhours. A total of 77 (33%)patientsdied. SIRS score and serum IL-4 concentration were measured in first hour after admission. Results: In 105 patients with SIRS score 3 and higher, initial measured IL-4 levels were significantly higher than in the group of remaining 129 patients. All nonsurvivals were in the first group, with SIRS score 3 and 4 and initial high level IL-4 concentration. The values of C reactive protein (CRP) measured after 48h, Acute Physiology and Chronic Health Evaluation (APACHE II) score on admission and Ranson score showed the similar correlation, but serum amylase level did not correlate significantly with Ranson score, IL-4 concentration and APACHE II score. Conclusion: The combinationof SIRS score on admission and IL-4 serum concentration can be early, predictor of illness severity and outcome in SAP.