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Effective synthesis of non-racemic prenalterol based on spontaneous resolution of 3-(4-hydroxyphenoxy)propane-1,2-diol

Authors :
Alexey V. Kurenkov
Zemfira A. Bredikhina
Alexander A. Bredikhin
Source :
Mendeleev Communications. 29:198-199
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Spontaneous resolution of rac-3-(4-hydroxyphenoxy)propane-1,2-diol has been successfully used in the synthesis of both enantiomers of chiral drug prenalterol.

Details

ISSN :
09599436
Volume :
29
Database :
OpenAIRE
Journal :
Mendeleev Communications
Accession number :
edsair.doi...........c002e2f8aa4e51094f5f91539574bf12
Full Text :
https://doi.org/10.1016/j.mencom.2019.03.028