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Direct demonstration of β-globin mRNA in homozygous Ferrara β0-thalassaemia patients
- Source :
- Nature. 266:231-234
- Publication Year :
- 1977
- Publisher :
- Springer Science and Business Media LLC, 1977.
-
Abstract
- In cases of β0- thalassaemia from Ferrara, Italy, the β-globin gene is transcribed into mRNA but no protein is synthesised. For these cases there is no hybridisation data suggesting a globin gene structural mutation. This again demonstrates the diverse molecular events which may cause this prevalent hereditary disease.
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 266
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi...........bf6d973897b72cdd8befccf3184266a5