Back to Search
Start Over
Unnatural tetradeoxy echinocandins produced by gene cluster design and heterologous expression
- Source :
- Organic & Biomolecular Chemistry. 21:3552-3556
- Publication Year :
- 2023
- Publisher :
- Royal Society of Chemistry (RSC), 2023.
-
Abstract
- Heterologous expression of the designed echinocandin biosynthetic gene cluster in the chassis strain results in the production of two novel tetradeoxy echinocandins, one of which has superior stability and antifungal activity to echinocandin B.
- Subjects :
- Organic Chemistry
Physical and Theoretical Chemistry
Biochemistry
Subjects
Details
- ISSN :
- 14770539 and 14770520
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Organic & Biomolecular Chemistry
- Accession number :
- edsair.doi...........bf2ee5a895932826e7473b94d789555f