Back to Search
Start Over
Developmental validation of 15 X chromosomal short tandem repeat markers
- Source :
- Forensic Science International: Genetics Supplement Series. 4:e142-e143
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- The use of X chromosomal short tandem repeat (STR) markers has been greatly increasing in the forensic setting. Using guidelines set forth previously for the validation of autosomal and Y STRs, aspects of the feasibility of routine X chromosomal STR use were evaluated. Two mini-X chromosomal STR multiplexes capable of amplifying 15 total markers were developed and utilized to determine allele nomenclature, allele/genotype frequencies, mutation rates, and linkage between markers. Additionally, a concordance study between these multiplexes and a commercially available kit was performed. Here, the authors present an overview of this extensive developmental validation study.
Details
- ISSN :
- 18751768
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- Forensic Science International: Genetics Supplement Series
- Accession number :
- edsair.doi...........bf135753966e3b229dc13bc694a6f19b
- Full Text :
- https://doi.org/10.1016/j.fsigss.2013.10.074