EFFECTS OF ACUTE SODIUM LOADING ON NCC ABUNDANCE AND PHOSPHORYLATION IN HYPERTENSIVES WITH RAISED ALDOSTERONE TO RENIN RATIO (ARR) IN HUMAN URINARY EXOSOMES

Objective:Primary aldosteronism (PA) is a common and potentially curable form of hypertension caused by excess and autonomous production of aldosterone by the adrenal gland. Renal salt homeostasis has profound effects on body fluid and blood pressure maintenance. In the renal distal tubule, aldoster