Evaluation of a new depot formulation of buprenorphine for sustained post-surgical analgesia in mouse femoral fracture models

Objectives: Adequate pain management is essential for ethical and scientific reasons in animal experiments. Choice of analgesics in fracture models is limited due to potential interference of anti-inflammatory drugs during the initial phase of healing. Depot formulations of Buprenorphine are only available [for full text, please go to the a.m. URL]