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Facile Enantiodivergent Approach to 5-Hydroxy-5,6-dihydro-2(1H)-pyridones. First Total Synthesis of Both Enantiomers of Pipermethystine
- Source :
- Organic Letters. 3:3381-3383
- Publication Year :
- 2001
- Publisher :
- American Chemical Society (ACS), 2001.
-
Abstract
- A novel enantiodivergent approach to 5-hydroxy-5,6-dihydro-2(1H)-pyridones using a ring closing metathesis and a lipase-mediated kinetic resolution as key steps is described and applied to the first synthesis of both enantiomers of pipermethystine.
Details
- ISSN :
- 15237052 and 15237060
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Organic Letters
- Accession number :
- edsair.doi...........bdb48e4965dc5f3cf9a80d21abd1600c
- Full Text :
- https://doi.org/10.1021/ol010183+