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Metabolic Syndrome among Ischaemic Stroke Patients in Ghana: The Possible Role of Renin and Aldosterone
- Source :
- OALib. :1-8
- Publication Year :
- 2017
- Publisher :
- Scientific Research Publishing, Inc., 2017.
-
Abstract
- Background: Both metabolic syndrome (MetSyn) and the Renin Angiotensin Aldosterone System (RAAS) are predictors of adverse outcomes in stroke patients. This study aimed at evaluating the association between RAAS and MetSyn among ischaemic stroke subjects in a tertiary hospital of Ghana from September 2015 to June 2016. Methodology: The study purposively recruited 252 Ghanaians comprising 132 ischaemic stroke patients and 120 apparently healthy control subjects. The participants were subjected to measurements of plasma renin, serum aldosterone, lipid profile, anthropometries and blood pressure. Results: MetSyn prevalence among the stroke subjects compared to the controls were 50.0% vs 8.3% (NCEP/ATP III), 71.2% vs 9.2 (IDF) and 71.2% vs 6.7% (H_MS). Both renin and aldosterone were significantly (p 3) aldosterone (aOR = 2.7, p = 0.008), obesity (aOR = 11.7, p = 0.004) and high triglyceride (aOR = 5.3, p p = 0.742) were independently associated with increasing odds of metabolic syndrome. Moreover, there was a significant (p p
- Subjects :
- medicine.medical_specialty
Aldosterone
medicine.diagnostic_test
business.industry
030204 cardiovascular system & hematology
medicine.disease
Plasma renin activity
Obesity
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Endocrinology
Blood pressure
chemistry
Internal medicine
Renin–angiotensin system
medicine
030212 general & internal medicine
Metabolic syndrome
business
Lipid profile
Stroke
Subjects
Details
- ISSN :
- 23339705 and 23339721
- Database :
- OpenAIRE
- Journal :
- OALib
- Accession number :
- edsair.doi...........bdb09577bf4f35f0bdd7a22ec8c19a97