Nutrition and Colorectal Cancer Pathogenesis

The common etiological factors for cancer are obesity, nutritional deficiencies, smoking, radiation, environmental toxins, sedentary lifestyle, and aging. These factors cause cancer by damaging genes in combination with existing genetic mutation within cells. Epidemiological studies have shown that diet containing fruits and vegetables reduce the risk of several types of cancer. High intake of fruits and vegetables has an active role in the prevention of chronic disease associated with oxidative stress-mediated carcinogenesis. World Health Organization projects 10,000,000 cases of cancer per year worldwide and 6,000,000 mortality from cancer per year worldwide. It also projected 15 million cases/year in 2020. Cancers vary on the basis of age, gender, race, and genetic predisposition.