Cardiovascular Risk Factors Insulin Resistance [IR], High Sensitivity C-reactive Protein (hs-CRP) and Fibrinogen in Pre- Menopausal women with Poly cystic ovarian syndrome (PCOS)

Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine pathies in women of reproductive age. We aimed to establish cardiovascular (CVD) risk factors in pre-menopausal Indian women with PCOS. Methods and Results: Study included 150 women (100 PCOS and 50 controls) from reproductive age (25-45 years). Both study groups were examined and analysed for anthropometric, clinical and biochemical parameters. Observations were subjected to statistical analysis using the descriptive statistics, Pearson’s coefficient of correlation and Multiple regression analysis. PCOS women presented with central adiposity (Waist circumference (cms) - 85.82 ± 12.16 v/s 78.84 ± 9.66p Conclusion: Obesity, IR, high pro-thrombotic and pro-inflammatory factors in Indian PCOS women indicate strong CVD risk and could cause cardiovascular complications in later life. Key words: Dyslipidemia, fibrinogen, HDL2c, hs-CRP, Insulin resistance, PCOS, sd LDLc.