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Cutaneous manifestations of polycystic ovary syndrome
- Source :
- Current Opinion in Endocrine and Metabolic Research. 12:49-52
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Hirsutism, acne, and/or female pattern hair loss are common cutaneous manifestations of polycystic ovary syndrome (PCOS). However, while hirsutism is mainly related to androgen excess, both acne and female pattern hair loss may often depend on cutaneous alterations that are not linked to hyperandrogenism or increased androgen sensitivity. Because both acne and female pattern hair loss cannot be considered a sign of hyperandrogenism, neither should be included in the diagnostic process of PCOS without demonstration of increased levels of circulating androgens. In addition, in patients with androgen-dependent acne, the concomitant proliferation of Propionibacterium acnes in skin may determine lack of response to antiandrogen or estroprogestin therapy. Similarly, in hyperandrogenic female pattern hair loss, scalp inflammation and/or mineral or vitamin deficiencies often prevent hair regrowth. To successfully treat these patients, it is necessary that endocrinologists and reproductive endocrinologists have a good understanding of the mechanisms determining cutaneous manifestations of PCOS.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
integumentary system
biology
business.industry
medicine.drug_class
Endocrinology, Diabetes and Metabolism
Hyperandrogenism
030209 endocrinology & metabolism
medicine.disease
Androgen Excess
Antiandrogen
biology.organism_classification
Polycystic ovary
Dermatology
03 medical and health sciences
Propionibacterium acnes
030104 developmental biology
0302 clinical medicine
Hair loss
medicine
business
Acne
hirsutism
Subjects
Details
- ISSN :
- 24519650
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Current Opinion in Endocrine and Metabolic Research
- Accession number :
- edsair.doi...........bc901937928a029a88b6881a5e3dedfa