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Age changes in fibronectin levels of the drainage system of the eye
- Source :
- Bulletin of Experimental Biology and Medicine. 108:1673-1675
- Publication Year :
- 1989
- Publisher :
- Springer Science and Business Media LLC, 1989.
-
Abstract
- Fibronectin is an extracellular adhesive glycoprotein which can bind selectively with type II collagen, the main constituent of the interstitial tissue of the trabecular system of the human eye [8], it can increase resistance to the outflow of aqueous humor [4, 5], and can thus raise the intraocular pressure. Fibronectin is found in the drainage system of healthy adults [4]. It is not clear, however, whether the content of this protein changes with age. This is an important concept in connection with the sharp increase observed in the fibronectin content during progression of primary open-angle glaucoma [2].
- Subjects :
- chemistry.chemical_classification
medicine.medical_specialty
Intraocular pressure
Age changes
genetic structures
biology
Chemistry
Type II collagen
food and beverages
Glaucoma
General Medicine
Anatomy
medicine.disease
eye diseases
General Biochemistry, Genetics and Molecular Biology
Fibronectin
Endocrinology
Interstitial tissue
Internal medicine
medicine
biology.protein
Extracellular
sense organs
Glycoprotein
Subjects
Details
- ISSN :
- 15738221 and 00074888
- Volume :
- 108
- Database :
- OpenAIRE
- Journal :
- Bulletin of Experimental Biology and Medicine
- Accession number :
- edsair.doi...........bbb8ca05e5fea682f084e664c0738e95