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Oral Drug Delivery to the Experimental Animals, A Mini Review
- Source :
- Global Drug Design & Development Review. :19-26
- Publication Year :
- 2016
- Publisher :
- Humanity Only - HO, 2016.
-
Abstract
- In several pharmacologic, pharmacology, and alternative medicine studies, oral administration of medication or test substances to experimental animals is needed. It is clinically sound and recommended to administer test substances to experimental animals along the same route that they are taken or expected to be taken by humans as general bioavailability; the pharmacology and pharmacology parameters obtained for the drug will depend significantly on the route chosen to administer it. The lack of ready access to high-quality oral tubing built for different species, as well as a widespread lack of technical expertise to properly use out-of-the-box techniques in this part of the world, has made this route controversial among medicine scientists. The typical problems and difficulties associated with the oral administration of test product solutions were avoided by mistreating either the syringe alone or incorporating it into the animals feeds or drinkables. This jury-rigged oral tubing was also used to ensure that the expected doses were correctly administered in each case.
- Subjects :
- business.industry
Medicine
Pharmacology
business
Oral retinoid
Mini review
Subjects
Details
- ISSN :
- 27884120 and 2788497X
- Database :
- OpenAIRE
- Journal :
- Global Drug Design & Development Review
- Accession number :
- edsair.doi...........bada836ee3b72069d8d2593e16981a38