ChemInform Abstract: A Novel Domino Reaction: Cyclization of Alkynyl Sulfides by Reaction with IPy2BF4

Authors :: Isidro Llorente
Gustavo P. Romanelli
Santiago Garcia‐Granda
José Barluenga
Esther García-Rodríguez
Lorenzo J. Alvarez-García
José M. González
Source :: ChemInform. 30
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: Formation of polycyclic structures within a few minutes: The intramolecular cyclization of diynes, activated by a benzenesulfenyl substituent, upon reaction with IPy2 BF4 proceeds as an efficient exo-endo coupling. A subsequent novel Friedel-Crafts-like ring closure provides the product [Eq. (1)]. Thus, intra- and intermolecular cyclizations can be carried out.

Subjects :: chemistry.chemical_compound
Cascade reaction
Chemistry
Intermolecular force
Intramolecular cyclization
Substituent
General Medicine
Ring (chemistry)
Medicinal chemistry

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