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A self-powered glucose biosensor device based on microfluidics using human blood
- Source :
- Journal of Power Sources. 515:230631
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- A self-powered glucose biosensor (SPGB) was developed based on biofuel cells (BFCs)and a microfluidic system as a suitable technology for high potential application in clinical diagnosis. In this work, a bioanode and biocathode were assembled by glucose oxidase-based and laccase-based electrodes, respectively, which were incorporated into a microfluidic system (m-SPGB), while the anolyte and catholyte were phosphate buffered at different pH values of 7.4 and 5.6, respectively. The m-SPGB showed a linear dynamic interval of 0–10 mM (R2 = 0.9907), a low limit of detection of 0.48 mM and a response to interfering species. Subsequently, human blood was used in the anolyte to quantify glucose molecules in real samples, obtaining a low relative error percentage when compared with a commercial glucometer. The coupling of the m-SPGB with a wireless electronic device allowed the detection and processing of the signal in the quantification of glucose directly without using a potentiostat/galvanostat. The promising results of the m-SPGB connected to a Wi-Fi electronic device are well suited for clinical application.
- Subjects :
- Detection limit
Biosensor device
biology
Renewable Energy, Sustainability and the Environment
Chemistry
Microfluidics
Energy Engineering and Power Technology
Signal
Potentiostat
Galvanostat
biology.protein
Glucose oxidase
Electrical and Electronic Engineering
Physical and Theoretical Chemistry
Biosensor
Biomedical engineering
Subjects
Details
- ISSN :
- 03787753
- Volume :
- 515
- Database :
- OpenAIRE
- Journal :
- Journal of Power Sources
- Accession number :
- edsair.doi...........b9ed490c131d67befb6160850d0cef2b