Ibuprofen for Early Treatment of Patent Ductus Arteriosus, a Randomized Multicenter Trial. • 1167

Introduction: Ibuprofen is emerging as a reasonable alternative to indomethacin for closing patent ductus arteriosus (PDA) in preterm infants with respiratory distress syndrome (RDS) (Arch Dis Child 97;76:F179). Moreover it has been shown that it does not reduce cerebral blood flow and causes less impairment of intestinal hemodynamics.