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GSK-3β sets Snail's pace
- Source :
- Nature Cell Biology. 6:913-915
- Publication Year :
- 2004
- Publisher :
- Springer Science and Business Media LLC, 2004.
-
Abstract
- Snail, a transcription factor that promotes epithelial-to-mesenchymal transitions during development, has also been implicated in human cancer. A new mechanism in which GSK-3β phosphorylation regulates the rate of Snail protein degradation may provide insight into invasion and the metastatic progression of tumours.
Details
- ISSN :
- 14764679 and 14657392
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Nature Cell Biology
- Accession number :
- edsair.doi...........b9933520e5dfb51d2e7a9cc91cf4e87f