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68Ga-DOTA-TOC-PET/CT detects heart metastases from ileal neuroendocrine tumors
- Source :
- Endocrine. 47:169-176
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- Metastases from ileal neuroendocrine tumors (NETs) to the myocardium are rare and generally seen in patients with widespread metastatic NET disease. The objectives of this investigation were to describe the frequency of intracardiac metastases in ileal NET patients examined by 68Ga-DOTA-TOC-PET/CT and to describe the cases in detail. All 68Ga-DOTA-TOC-PET/CT examinations performed at the Karolinska University Hospital since 2010 until April 2012 were reviewed. In all, 128 out of 337 examinations were in patients with ileal NETs. Four patients had seven myocardiac metastases, yielding a frequency of 4.3 % in patients with ileal NETs. One patient had cardiac surgery while three were treated with somatostatin analogs. The cardiac metastases did not affect the patients’ activity of daily life. 68Ga-DOTA-TOC-PET/CT is an established imaging modality in identifying cardiac metastases in ileal NETs. Prospective studies are needed to confirm the true clinical value of 68Ga-DOTA-TOC-PET/CT in detecting cardiac metastases in both ileal and non-ileal NETs.
- Subjects :
- medicine.medical_specialty
PET-CT
business.industry
Endocrinology, Diabetes and Metabolism
Neuroendocrine tumors
University hospital
medicine.disease
Intracardiac injection
Cardiac surgery
chemistry.chemical_compound
Endocrinology
Somatostatin
chemistry
DOTA
Medicine
Radiology
Prospective cohort study
business
Subjects
Details
- ISSN :
- 15590100 and 1355008X
- Volume :
- 47
- Database :
- OpenAIRE
- Journal :
- Endocrine
- Accession number :
- edsair.doi...........b97071775f415968d6e752342a428f8b