Back to Search Start Over

AB0618 Prevalence of hypovitaminosis d in adults with systemic lupus erythematosus and the relationship with sledai 2k in patients treated in two rheumatology services, bogota 2017

Authors :
Juan Carlos Aguirre García
K.A. Guzman Moreno
Vanessa Cadavid
María C. Mejía
Luis Gabriel Piñeros
Aníbal A. Teherán
J. Bustillo
R.A. Guzman Moreno
Luis Miguel Pombo
Source :
SLE, Sjögren’s and APS – clinical aspects (other than treatment).
Publication Year :
2018
Publisher :
BMJ Publishing Group Ltd and European League Against Rheumatism, 2018.

Abstract

Background Vitamin D is a steroid hormone with pleiotropic effects on physiological processes. Among others, immune system regulation and their analogues prevent symptom development of autoimmune diseases such as SLE. A previous research in a colombian clinic found a prevalence of hipovitaminosis D of 87% in healthy population, but hypovitaminosis D is higher in SLE patients than healthy controls. Objectives To establish the prevalence of hypovitaminosis D in patients with SLE and relationship with SLEDAI – 2K. Methods A cross sectional study was carried out. 80 medical records with a diagnoses of SLE o CIE-10 M30-M36 were identified and we included patients>18 years of age who meet at least 4 of the 11 criteria to diagnoses of SLE for medical record. The analysis included means, DS and Kruskall Wallis with p-value Results The majority of patients are women (94%), with an average age of 39.9 years, married (41%), with secondary education (56.7%) and different occupations. It was found that the patients with higher activity, had lower vitamin D levels. Additionally, if the patient had lupus nephritis, vitamin D levels decreased even more. Conclusions Patients with active systemic lupus Erythematosus, (SLE) have hypovitaminosis D more frequently and we noticed that patients with renal involvement have the lowest levels of vitamin D, which justifies a later analysis. References [1] American College of Rheumatology. Guidelines for referral and management of systemic lupus erythematosus in adults. Arthritis Rheum. 1999Sep;42(9):1785–96. [2] Simioni J, Heimovski F, Skare T. On lupus, vitamin D and leukopenia. 2016;56(3):206–211. [3] Guzman R.A, Pineros L.G, Theran A, Flechas J, Mejia M. AB0795 Hypovitaminosis D and Calcium Intake of Adult Population in Bogota (DICAVITD). Ann Rheum Dis2016;75:1175–1176. [4] Alele J., et al. Autoimmun Rev2010;9:137–39. [5] Dall, era M., et al. in KelleyF Philadelphia 2017; 1368–89. Disclosure of Interest None declared

Details

Database :
OpenAIRE
Journal :
SLE, Sjögren’s and APS – clinical aspects (other than treatment)
Accession number :
edsair.doi...........b90b49bff8a20ba5ac478284274aa660
Full Text :
https://doi.org/10.1136/annrheumdis-2018-eular.3990