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The Influence of National Guidelines on the Management of Community-Acquired Pneumonia in Children. Do Pediatricians Follow the Recommendations?
- Source :
- Advances in Experimental Medicine and Biology ISBN: 9783030327873
- Publication Year :
- 2019
- Publisher :
- Springer International Publishing, 2019.
-
Abstract
- This is a retrospective study whose main objective was to analyze the influence of the Polish Guidelines for the Management of Respiratory Tract Infections of 2010 (PGMRTI) on in-hospital treatment of children with community-acquired pneumonia (CAP). Files from four Warsaw hospitals were reviewed to identify children with uncomplicated CAP, treated before (2008–2009) (pre-PGMRTI) and after (2011–2012) (post-PGMRTI) publication of the guidelines. Predefined data on the management were compared. A cohort of 2,359 children (1,081 pre-PGMRTI and 1,278 post-PGMRTI) was included. We found that co-amoxiclav was the most common first-line therapy in children >3 months of age (34.6% and 40.4% pre- and post-PGMRTI, respectively), followed by cefuroxime (31.8% and 20.9% pre- and post-PGMRTI, respectively; p < 0.0001) and macrolides (17.4% and 24.5% pre- and post-PGMRTI, respectively; p < 0.0001). Amoxicillin was rarely used (5.4% and 4.9%, pre- and post-PGMRTI, respectively). The study revealed an overuse of inhaled bronchodilators, corticosteroids, and mucoactive drugs. Blood diagnostic tests were applied to a significant percentage of patients: blood cultures (41.2% and 44.5% pre-and post-PGMRTI, respectively) and serology for atypical pathogens (27.9% and 44.9% pre-and post-PGMRTI, respectively; p < 0.0001). The number of follow-up chest X-rays increased (30.5% and 53.8% pre- and post-PGMRTI, respectively; p < 0.0001). In conclusion, the study demonstrates an unsatisfactory influence of the guidelines on in-hospital management of CAP in children. Despite an explicit recommendation for the use of amoxicillin, it was still underused. Other methods of education and guideline dissemination are needed to optimize the prescribing of antibiotics.
- Subjects :
- medicine.medical_specialty
Respiratory tract infections
business.industry
Retrospective cohort study
Guideline
Amoxicillin
medicine.disease
03 medical and health sciences
Pneumonia
0302 clinical medicine
Community-acquired pneumonia
Internal medicine
Cohort
medicine
030212 general & internal medicine
business
Cefuroxime
medicine.drug
Subjects
Details
- ISBN :
- 978-3-030-32787-3
- ISBNs :
- 9783030327873
- Database :
- OpenAIRE
- Journal :
- Advances in Experimental Medicine and Biology ISBN: 9783030327873
- Accession number :
- edsair.doi...........b876e932be0781f218457b377359199f