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Concise Synthesis of Anserine: Efficient Solvent Tuning in Asymmetric Hydrogenation Reaction
- Source :
- Synlett. 27:2734-2736
- Publication Year :
- 2016
- Publisher :
- Georg Thieme Verlag KG, 2016.
-
Abstract
- A concise synthesis of anserine and related compounds was accomplished by Et-DuPhos-Rh-catalyzed asymmetric hydrogenation of dehydrohistidine derivatives in 2,2,2-trifluoroethanol, which played a key role in improving the yield and selectivity.
Details
- ISSN :
- 14372096 and 09365214
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Synlett
- Accession number :
- edsair.doi...........b838082f29a1882d4b42ae9e4a2fc619
- Full Text :
- https://doi.org/10.1055/s-0035-1562796