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Confirmation of genetic risk markers of platinum-induced ototoxicity

Authors :
Tillmanns, Amelie
Parfitt, Ross
Matulat, Peter
Abdel-Kahaar, Emaad
Maier, Lara
Zolk, Oliver
Elsner, Susanne
Wolschon, Eva-Maria
Kuehni, Claudia E.
Kuonen, Rahel
Weiss, Annette
Garré, Marie-Luisa
Kepak, Tomas
Kepakova, Katerina
Kruseova, Jarmila
Luks, Ales
Falck Winther, Jeanette
Kenborg, Line
Lackner, Herwig
Bielack, Stefan
van den Heuvel-Eibrink, Marry
Calaminus, Gabriele
Baust, Katja
Beck, Jörn
Kremer, Leontien
Clemens, Eva
Langer, Thorsten
am Zehnhoff-Dinnesen, Antoinette
PanCareLIFE Consortium
Publisher :
German Medical Science GMS Publishing House

Abstract

Background Platinum compounds such as cisplatin or carboplatin are potent antineoplastic agents widely used for a variety of cancer types. Unfortunately, their use leads to dose-limiting side effects such as ototoxicity. Our study aimed at investigating the predictive value of 11 candidate genetic[for full text, please go to the a.m. URL]<br />36. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP)

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi...........b73a0242088410bc40fdb5ff97e4a758