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Considerations for tisagenlecleucel dosing rationale

Authors :
Constantine S. Tam
Edmund K. Waller
Karen Thudium Mueller
Gregory A. Yanik
Ulrich Jäger
Peter Borchmann
Jason Hamilton
Michael R. Bishop
André Baruchel
Mariana Cota
Joseph P. McGuirk
Rakesh Awasthi
Michael Boyer
Edward K Waldron
Samantha Jaglowski
Heather E. Stefanski
G.D. Myers
Lida Bubuteishvili-Pacaud
Susana Rives
Source :
Journal of Clinical Oncology. 36:e15056-e15056
Publication Year :
2018
Publisher :
American Society of Clinical Oncology (ASCO), 2018.

Abstract

e15056Background: Analyses supporting a safe and efficacious dose for CAR therapies are not well defined and vary across CAR-T programs. These analyses present key considerations to support tisagen...

Details

ISSN :
15277755 and 0732183X
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........b676863283d88048bb89be9c16736cf2