Caracterização farmacológica das gliflozinas em plaquetas humanas isoladas: avaliação in vitro

Gliflozins are relatively recent drugs, and have been incorporated into the arsenal of the treatment of diabetics. To these, a favorable cardiovascular effect was attributed to clinical data from diabetic patients treated with similar therapies compared to glyphlozines. The project sought to investigate the performance of these drugs in platelets, since they are emblematic figures in the main pathophysiology of the disease that has the highest cause of death in the world: Coronary artery disease.