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Interdigitating dendritic cell sarcoma of the tonsil
- Source :
- Asia-Pacific Journal of Clinical Oncology. 6:144-148
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare malignancy derived from antigen-presenting cells, with 55 cases reported thus far. A standard treatment modality is still being debated. This report describes a 56-year-old female who presented with right tonsillar enlargement and right submandibular swelling for 6 months. Treatment with empiric antibiotics did not result in improvement of her symptoms. Fine needle aspiration of the tonsil revealed no malignant cells. Tonsillectomy was eventually performed due to persistent symptoms. Based on microscopic findings, immunohistochemical stains, and review of the literature, the present case was finally diagnosed as IDCS of the tonsil with cervical lymph node involvement. The patient received four cycles of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) chemotherapy, and a clinically complete response was achieved followed by adjuvant radiation.
- Subjects :
- Vincristine
Pathology
medicine.medical_specialty
medicine.diagnostic_test
business.industry
medicine.medical_treatment
General Medicine
medicine.disease
Malignancy
Tonsillar Neoplasm
Radiation therapy
Fine-needle aspiration
medicine.anatomical_structure
Oncology
Interdigitating dendritic cell sarcoma
Tonsil
medicine
business
Lymph node
medicine.drug
Subjects
Details
- ISSN :
- 17437555
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Asia-Pacific Journal of Clinical Oncology
- Accession number :
- edsair.doi...........b6265937ef77140cc46092768477bdf3