Microbial transformation of 2,3-dihydro-3-methoxywithaferin-A by Cunninghamella elegans

Authors :: J. Fuska
Bohumil Proksa
Alžbeta Fusková
Maria Šturdícová
Source :: Phytochemistry. 25:1613-1615
Publication Year :: 1986
Publisher :: Elsevier BV, 1986.
Abstract: Cunninghamella elegans (NRRL 1393) transformed 2,3-dihydro-3-methoxywithaferin-A to 2,3-dihydro-12β-hydroxy-3-methoxywithaferin-A. Both compounds inhibited the growth and biochemical functions of in vitro grown P388 lympholeukemic cells.

Subjects :: Cunninghamella elegans
biology
medicine.medical_treatment
Microbial transformation
Biological activity
Plant Science
General Medicine
Horticulture
biology.organism_classification
Biochemistry
In vitro
Steroid
carbohydrates (lipids)
Biotransformation
medicine
heterocyclic compounds
P388 leukemia
Molecular Biology

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