Back to Search Start Over

Hepatotoxicity and Toxicology of In Vivo Lentiviral Vector Administration in Healthy and Liver-Injury Mouse Models

Authors :
Raymond D. Hickey
Kari L. Allen
Joseph B. Lillegard
Robert A. Kaiser
Zeji Du
Jennifer Anne Chilton
Clara T. Nicolas
Source :
Human Gene Therapy Clinical Development. 30:57-66
Publication Year :
2019
Publisher :
Mary Ann Liebert Inc, 2019.

Abstract

General safety and toxicology assessments supporting in vivo lentiviral vector-based therapeutic development are sparse. We have previously demonstrated the efficacy of a lentiviral vector expressi...

Details

ISSN :
23248645 and 23248637
Volume :
30
Database :
OpenAIRE
Journal :
Human Gene Therapy Clinical Development
Accession number :
edsair.doi...........b56ebf39e4a7c6cadbc82986f5cd63bb