Back to Search Start Over

P.2.013 Dopamine D4 receptor activation improves performance in a rat model of ADHD

Authors :
John Gigg
L. Adamson
Michael K. Harte
Andrew Hayward
Joanna C. Neill
W. El-Deredy
Anneka Tomlinson
Source :
European Neuropsychopharmacology. 24:S41-S42
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

Conclusions: The ultimate goal of our study was to determine whether remoxipride had the ability to improve recognition memory in rats. Even if our results did not show any significant enhancement in recognition memory by remoxipride, the up-going trend is evident. Stipulated this tendency is accurate, remoxiprides mechanism of action would be an invaluable tool if implemented in the pharmaceutical industry, as it might enable the development of novel pro-cognitive agents, which in turn may improve the quality of life of millions of patients suffering from schizophrenia.

Details

ISSN :
0924977X
Volume :
24
Database :
OpenAIRE
Journal :
European Neuropsychopharmacology
Accession number :
edsair.doi...........b5233641e6260b63a825252a6a0d0a7e
Full Text :
https://doi.org/10.1016/s0924-977x(14)70046-x