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O3‐05–04: The 8‐hydroxyquinoline analog PBT2 rapidly restores cognition and reduces soluble Abeta in Alzheimer transgenic mice

Authors :
Joseph A. Nicolazzo
David Finkelstein
Qiao-Xin Li
Roberto Cappai
Karolina Deleva
Craig W. Ritchie
Mikhalina Cortes
Colin L. Masters
Simon Wilkins
Penny Huggins
Elysia Robb
Gaik Beng Kok
Elisabeth Gautier
Ashley I. Bush
Robert A. Cherny
Irene Volitakis
Paul A. Adlard
Susan A. Charman
Xiang Liu
Kevin J. Barnham
Katrina M. Laughton
Keyla Perez
Rudi E. Tanzi
Jack Gordon Parsons
Jeffrey P. Smith
Source :
Alzheimer's & Dementia. 4
Publication Year :
2008
Publisher :
Wiley, 2008.

Abstract

Robert A. Cherny, Paul A. Adlard, David I. Finkelstein, Elisabeth Gautier, Penny Huggins, Jack Parsons, Craig W. Ritchie, Elysia Robb, Mikhalina Cortes, Irene Volitakis, Xiang Liu, Jeffrey P. Smith, Keyla Perez, Katrina Laughton, Qiao-Xin Li, Susan A. Charman, Joseph A. Nicolazzo, Simon Wilkins, Karolina Deleva, Gaik Kok, Roberto Cappai, Rudi E. Tanzi, Colin L. Masters, Kevin J. Barnham, Ashley I. Bush, The Mental Health Research Institute of Victoria & The University of Melbourne, Parkville, VIC, Australia; MHRI & The University of Melbourne, Parkville, Australia; Prana Biotechnology Ltd, Parkville, Australia; Imperial College London, London, United Kingdom; MHRI, Parkville, Australia; The University of Melbourne, Parkville, Australia; Centre for Drug Candidate Optimisation, Parkville, Australia; Bio 21 Institute, The University of Melbourne, Parkville, Australia; Genetics & Aging Research Unit, MGH, Boston, MA, USA. Contact e-mail: rcherny@mhri.edu.au

Details

ISSN :
15525279 and 15525260
Volume :
4
Database :
OpenAIRE
Journal :
Alzheimer's & Dementia
Accession number :
edsair.doi...........b3fac2c48197da8c6f8f26f9f6bf1cac
Full Text :
https://doi.org/10.1016/j.jalz.2008.05.444